Eye color (blue, green/hazel, brown)
HERC2 + OCA2 · Physical · Evidence ★★★★★
Eye color is mostly set by a HERC2 switch that turns brown pigment up or down, with an OCA2 variant that can nudge a result toward green or hazel. Reading the two together predicts color better than the main switch alone.
Possible results
Brown eyes likely. Your HERC2 switch keeps brown pigment turned up and you don't carry the OCA2 green-shifter, so brown eyes are very likely. Other genes can still add subtle green or hazel tones.
Brown likely, possible green tint. Your HERC2 switch favors brown pigment, but the OCA2 green-shifting variant you carry can lighten that toward hazel or green-brown. Brown is still the most likely base color.
Brown or green likely. Your HERC2 switch is half-on, the intermediate setting, without the OCA2 green-shifter. People with this mix usually have brown, sometimes green or hazel eyes, because the brown-pigment side tends to win out.
Green or hazel likely. Your HERC2 switch is in the intermediate setting and you carry the OCA2 green-shifting variant, a combination that often lands on green or hazel. Outcomes in this middle zone are the least certain of all eye colors.
Green or hazel possible (blue base). Your HERC2 switch points toward blue, but you also carry the OCA2 modifier variant that can add green tones. This is the classic 'expected blue, came out green' combination, so green or light hazel is a real possibility alongside blue.
Blue eyes likely. Your HERC2 switch is in the low-pigment setting that most strongly predicts blue eyes, and you don't carry the OCA2 modifier that pushes toward green. Blue is the most likely outcome, though other pigment genes can still shift the final shade.
Evidence & sources
This panel reads HERC2, OCA2 R419Q.
Combines the main HERC2 blue/brown switch with the OCA2 green/hazel modifier. Eye color draws on several more pigment genes not tested here, so green and hazel in particular are only rough predictions.
Related
Body mass index · Earwax type / body odor · Endurance / aerobic capacity (PPARGC1A) · Freckling / sun sensitivity · Height · Muscle fiber type (power vs endurance) · Skin pigmentation (light vs dark)
References: HERC2 · OCA2 R419Q
Educational and informational only, not medical advice.
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