All traits

Depression

Polygenic score · Health · 17 variants

Major depression has a modest, highly polygenic genetic component. This score sums many small-effect variants into a rough susceptibility estimate.

Evidence & sources

This polygenic score combines 17 common variants.

A higher score means higher depression risk.

This score was developed mostly in people of European ancestry (100%), so it may be less accurate for other backgrounds.

Related

APOE type (Alzheimer's & cholesterol) · Asthma · Atrial fibrillation risk (4q25) · Autoimmune protection (IL23R R381Q) · Coronary artery disease · HbA1c (blood sugar) · Venous thromboembolism (clots)

References: PGS Catalog

Educational and informational only, not medical advice.

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